Five matches separate Barcelona from European glory and Ernesto Valverde's side have plenty of weapons at their disposal if they are to come out on top in the competition.
They will all play into their hands as they look to lift the trophy on June 1 at the Estadio Wanda Metropolitano.
We look at seven reasons to believe that they will take major honours once more.
The Messi factor
A Messi on form is synonymous with a fearsome Barcelona.
The Argentine wants this Champions League badly and hasn't been in this kind of form for some time.
He is the competition's joint-top scorer with eight goals and has an ability to open up games that cannot be questioned.
Against Lyon, he was seen pressing and pitching in with the dirty work when necessary.
If he remains on form, the end result may be lifting the title on June 1 at the Estadio Wanda Metropolitano.
The Camp Nou is untouchable
With the victory against the French side, Barcelona set a new record in the competition with 30 home games without tasting defeat.
There have been 27 victories and three draws in that time, surpassing the 29 undefeated games that previous record holders Bayern Munich managed.
Although Barcelona have doubts around them on the road, the home factor is a big boost in decisive moments.
It is scary for opposition teams to step onto the Camp Nou turf and that can be a decisive factor.
The Champions League's best goalkeeper
After Manuel Neuer exited with an unfortunate performance against Liverpool